What are the current recommendations regarding aspirin for
the prevention of preeclampsia?
The results of a systematic review suggests that the use of low-dose aspirin is associated with a reduction in the relative risk of preeclampsia. There is no difference in effect whether low-dose aspirin is started before or after 20 weeks gestation .
As of this writing The Society of Obstetricians and Gynaecologists of Canada and the American College of Chest Physicians recommend low-dose aspirin throughout pregnancy, starting from the second
The National Institute for Health and Clinical Excellence (NICE) recommends women at high risk of pre-eclampsia should take 75 mg of aspirin daily from 12 weeks until the birth of the baby
Women at high risk include: hypertensive disease during a previous pregnancy ,chronic kidney disease ,autoimmune disease such as systemic lupus erythematosis or antiphospholipid syndrome , type 1 or type 2 diabetes and chronic hypertension
In addition NICE recommends women with more than one moderate risk factor for pre-eclampsia should to take 75 mg of aspirin daily from 12 weeks until the birth of the baby. Moderate risk factors are: first pregnancy , age 40 years or older, pregnancy interval of more than 10 years , body mass index (BMI) of 35 kg/m2 or more at first visit , family history of pre-eclampsia multiple pregnancy.
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