Reference Values During Pregnancy

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Activated partial thromboplastin time , aPTT (whole blood)

   Units Nonpregnant Adult First Trimester Second Trimester Third Trimester
Seconds 26.3 - 39.4 24.3 - 38.9 24.2 - 38.1
24.7 - 35.0

Causes of a prolonged aPTT include, but are not limited to, heparin, coumadin, lupus anticoagulant, coagulation factor deficiencies , and specific coagulation factor inhibitors


Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2009 Dec;114(6):1326-31. PMID:19935037
Wallach, J. Interpretation of Diagnostic Tests, Eighth ed. Lippincott Williams & Wilkins, 2007 Fischbach FT, Dunning MB III, eds. A Manual of Laboratory and Diagnostic Tests, 7th ed. Philadelphia, Lippincott Williams and Wilkins,2004


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