A CVR > 1.6 or a CPAM with a dominant large
cyst* increases risk of developing hydrops. Lesions with a CVR
of > 1.6 may be followed 2 to 3 times per week.
is dominant if it constitutes greater
than a third the size of the CPAM.
These cysts may increase rapidly in size from fluid accumulation.
The calculator below may be used to estimate the CVR.
1. Cass DL, et al. Prenatal diagnosis and outcome of fetal
lung masses. J Pediatr Surg. 2011 Feb;46(2):292-8.PMID:
2. Crombleholme TM, Cystic adenomatoid malformation volume ratio predicts
outcome in prenatally diagnosed cystic adenomatoid malformation of the
lung.J Pediatr Surg. 2002 Mar;37(3):331-8.
3. Adzick NS, Flake AW, Crombleholme TM. Management of congenital lung
lesions. Sem Pediatr Surg. 2003;12:10–16.
Di Prima FA, Bet al., Antenatally diagnosed congenital
cystic adenomatoid malformations (CCAM): Research Review.
J Prenat Med. 2012 Apr;6(2):22-30.PMID: 22905308
All calculations must be confirmed before use. The suggested results are not a substitute for clinical
judgment. Neither Perinatology.com nor any other party involved in the preparation or publication of this site shall be liable for any special, consequential,
or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.