The proximal middle cerebral artery is
enlarged to to occupy more than 50% of the image and is sampled 2 mm after
its origin from the internal carotid artery. The angle of the ultrasound beam and the direction of blood flow should be zero degrees. The risk of anemia is highest in fetuses with a
pre-transfusion peak systolic velocity of 1.5 times the median or higher.
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2. Delle Chiaie L, et al., Prediction of fetal anemia with
Doppler measurement of the middle cerebral artery peak systolic velocity
in pregnancies complicated by maternal blood group alloimmunization or
parvovirus B19 infection.
Ultrasound Obstet Gynecol. 2001;18:232-6.
3. Nishie EN, A comparison between middle cerebral artery
peak systolic velocity and amniotic fluid optical density at 450 nm in the
prediction of fetal anemia.
Am J Obstet Gynecol. 2003 ;188:214-9.
4. Pereira L, et al., Conventional management of maternal
red cell alloimmunization compared with management by Doppler assessment
of middle cerebral artery peak systolic velocity.
Am J Obstet Gynecol. 2003 ;189:1002-6.
5. Abel DE, et al. ,Ultrasound assessment of the fetal
middle cerebral artery peak systolic velocity: A comparison of the
near-field versus far-field vessel.
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6. Alshimmiri MM,et al., Prediction of fetal anemia by
middle cerebral artery peak systolic velocity in pregnancies complicated
by rhesus isoimmunization.
J Perinatol. 2003;23:536-40.
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