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  Expected Peak Velocity of Systolic Blood Flow in
  the MCA as a Function of Gestational Age

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      The middle cerebral artery is examined close to its origin in the internal carotid artery. The angle of the ultrasound beam and the direction of blood flow should be zero degrees. The risk of anemia is highest in fetuses with a pre-transfusion peak systolic velocity of 1.5 times the median or higher.
       
      ENTER:
      Gestational age (weeks) 

      Observed MCA Peak Systolic Velocity (cm/sec)


       

           

      Calculations:
       The Median Peak Systolic Velocity for this age is  
      Your measurement is  Multiples of Median

      REFERENCES:

      1. Mari G. Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. N Engl J Med 2000; 342:9-14 Obstet. 1998 ;63:195-202. MEDLINE
      2. Delle Chiaie L, et al., Prediction of fetal anemia with Doppler measurement of the middle cerebral artery peak systolic velocity in pregnancies complicated by maternal blood group alloimmunization or parvovirus B19 infection. Ultrasound Obstet Gynecol. 2001;18:232-6. MEDLINE
      3. Nishie EN, A comparison between middle cerebral artery peak systolic velocity and amniotic fluid optical density at 450 nm in the prediction of fetal anemia. Am J Obstet Gynecol. 2003 ;188:214-9. MEDLINE
      4. Pereira L, et al., Conventional management of maternal red cell alloimmunization compared with management by Doppler assessment of middle cerebral artery peak systolic velocity. Am J Obstet Gynecol. 2003 ;189:1002-6. MEDLINE
      5. Abel DE, et al. ,Ultrasound assessment of the fetal middle cerebral artery peak systolic velocity: A comparison of the near-field versus far-field vessel. Am J Obstet Gynecol. 2003;189:986-9. MEDLINE
      6. Alshimmiri MM,et al., Prediction of fetal anemia by middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus isoimmunization. J Perinatol. 2003;23:536-40. MEDLINE

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    Created: 12/18/2001
    Last update: 12/01/2003