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  "Caritis" Ritodrine Protocol

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    • Begin ritodrine infusion at 50 mcg/min(0.05mg/min)
    • Increase by 50 mcg/min every 20 minutes
    • Maximum dose: 350 mcg/min
    • If contractions less frequent than every 10 minutes, wait another 20 minutes before increasing the dose
    • Once labor is stopped, maintain infusion rate for 1 hour;then reduce every 20 minutes to the lowest rate that inhibits contractions adequately
    • Continue this maintenance rate for 12 hours
    • Discontinue or decrease dosage for maternal pulse >150 BPM,FHR>200 BPM,> 6 maternal or fetal PVCs/min,SBP> 180 mm Hg, DBP< 40 mm Hg.
    • Cardiac monitor. Serum K+ and glucose q 4 hr.

    • REF:Caritis S et al.:Pharmacodynamics of ritodrine in pregnant women during preterm labor.Am J Obstet Gynecol 147:752,1983

       

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    Created: 4/12/2001
    Last update: 11/30/2002